|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Intrinsic Choroidal Neurons (ICN) in the Human Eye: Projections, Targets, and Basic Electrophysiological Data
Schrödl F.1, De Laet A.2,3, Tassignon M. J.4, Van Bogaert P.-P.2, Brehmer A.1, Neuhuber W. L.1, Timmermans J.-P.3
Purpose: The chemical coding of intrinsic choroidal neurons (ICN) has features in common with extrinsic fibers (e.g. originating from the pterygopalatine ganglion) making it impossible to assess whether a nNOS/VIP-immunoreactive nerve fiber is of intrinsic or extrinsic origin. Electrophysiological single cell injections allow the iontophoretical filling of neurons, thus visualization of projections of these cells and defining the origin of target innervation. The aim of this investigation was to adopt this technique to the study of human choroids.