|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Recent Developments in the Non-invasive diagnosis of Macular Diseases
During the past years the diagnosis and management of macular diseases has been improved by the development of various innovative diagnostic tools. Especially, progresses in the scanning laser technique and optical coherence topography have opened new diagnostic possibilities. The scanning laser technique is applied mainly for fluorescein and ICG angiography. Other applications include assessment of retinal and choroidal hemodynamics (e.g. high speed angiography), imaging of retinal autofluorescence, measurement of macular pigment density, microperimetry, and electrophysiology. Optical coherence topography can image retinal structures in vivo with a high resolution. Cross-sectional images of the retina are produced using the optical backscattering of light. The anatomic layers within the retina can be differentiated and retinal thickness can be measured. Especially, the assessment of retinal thickness is a new technique for diagnosis and management of macular edema. Other instruments for assessment of retinal thickness in macular edema are the Retinal Thickness Analyzer (RTA) and the Heidelberg Retina Tomograph (HRT II) with the macular software. Both instruments produce retinal thickness or edema maps. Recently, the combination of scanning laser and OCT technique have been developed. This new imaging technique may provide further insights into macular pathology in the near future.