|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
In vitro Cornea Model Corneal Re-epithelisation after Mechanical Trauma
Nietgen A. M.1, Keller-Kuckelkorn G. K.1, Salla S.1, Kondring B.1, Frentz W.2, Reim M.1, Schrage N. F.1
Purpose: The avascular cornea is exposed to external influences and is vulnerable to chemical irritation. The biological response to such traumas provoces changes in cellular function within the cornea and the release of inflammatory mediators that initiate a secondary inflammatory response in the adjacent conjunctiva. According to animal experiments we attempt to demonstrate that the ex vivo cornea offers a suitable model to investigate external eye damage.