The Dry Eye and the Gastral Helicobacter Pylori Infection
Blomberg L.1, Hauschild S.1, Kilian K.2, Brewitt H.1
1Department of Ophthalmology, Medizinische Hochschule Hannover, Hannover
2Medical Center of the Bundeswehr, Hannover
Purpose: In some single recent publications the Helicobacter pylori (H.P.) Infection was related to Sjögren syndrome and Acne rosacea. These diseases are well known to be connected with the dry eye syndrome. Moreover, a role for H. pylori has also been postulated in the MALT-Lymphoma of the stomach and coronary heart disease.
Method: Patients with dyspepsia, who are elected for gastroscopy, are interviewed prospectively by an specific evaluation form for the dry eye concerning their subjective symptoms. A standard clinical examination is made and patients are classified for a certain sicca-stage. After gastroscopy and a positive helicobacter-serology an eradication is recommended.
Results: 53 Patients (106 eyes) were examined prospectively. 33 patients were H.P. negative, 20 H.P. positive. The patients age differs between 20 and 66 years (mean age 36 years). In the statistic evaluation, the H.P. positive patients show increased signs of quantitative moisturizing disorders (e.g. reduced schirmers test). Qualitative parameters as break up time and lid parallel conjunctival folds showed no relation to H.P. infection but were significantly age related.
Conclusions: An epidemiological association between helicobacter pylori infection and the dry eye syndrome seems
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