Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


Hotelbuchung
   Hotel Registration
Grußwort
   Welcome address
Beteiligte Gesellschaften
   Societies involved
DOG Information
   DOG Information
Eröffnung des Kongresses
   Opening Ceremony
Preise
   Awards
Ablauf der Tagung 2003
   General overview of congress
Lageplan der Räumlichkeiten
   Map of Congress Center
Wissenschaftliche Themen
   Scientific topics
Symposien
   Symposia
Wissenschaftliches Programm
   Scientific program
Posterpräsentationen
   Poster Presentation
Kurse
   Courses
Begleitende Veranstaltungen
   Accompanying program
Arbeitssitzungen
   Working sessions
Rahmenprogramm
   Social program
Allgemeine Informationen
   General Information
Autorenindex
   Index of Authors
Industrieaussteller
   Commercial exhibitors
Sponsoren
   Sponsors
Impressum



DOG Homepage


Abstract
Abstract

Graft Ulcers after Penetrating Keratoplasty due to Herpetic Inflammation - Detection by Polymerase-Chain-Reaction (PCR)

Sengler U.1, Reinhard T.2, Adams O.3, Schilgen G.1, Sundmacher R.1
1Eye Hospital and Institute for Med. Microbiology und 3Virology, Heinrich-Heine University, Duesseldorf
2Eye Hospital, Albert-Ludwigs-University, Freiburg

Purpose: An ulcer on a corneal graft is a serious complication after keratoplasty. Various reasons must be taken into account: Dry eye syndrom, suture loosening, immune reaction, bacterial infection, recurrences of rheumatic or herpetic eye disease. Though the latter shows some clinical particularities, the clinical findings are not so characteristic as in herpetic eye disease without a corneal graft. If a herpetic inflammation as underlying disease for the keratoplasty is not known or even suspected, serious complications may result.
Method: We describe 11 patients presenting with graft ulcers after penetrating keratoplasty. With some patients herpetic eye disease was suspected as they had had herpetic inflammations before, with others the possibility of herpetic infection had never been thought of. Some of these patients experienced corneal ulceration and even lytic infiltration of the graft repeatedly. Material from the ulceration harvested by a corneal swab was examined by PCR for Herpes simplex virus (HSV).
Results: With all patients the PCR was positive for HSV type 1. The ulceration was located at the margin of the corneal gr


Zurück | Back