Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Choroidal Effusion with Exudative Retinal Detachment Caused by Superior Ophthalmic Vein Thrombosis in a Patient Suffering from APC Resistance

Nestler A., Foja C.
Klinik und Poliklinik für Augenheilkunde, Universität Leipzig

Purpose: Factor V Leiden heterozygotes experience a three- to six-fold increase in thrombotic events. However there are no reports about isolated superior ophthalmic vein thrombosis in patients suffering from APC resistance yet.
Method: Casereport about a 79-year old female patient who was referred to our clinic because of an exudative retinal detachment.
Results: Visual acuity in the affected left pseudophakic eye was 20/200. There was a conspicuous unilateral dilation of episcleral vessels. In the binocular ophthalmoscopy we found a retinal detachment of the lower hemisphere reaching the macula but no retinal tear. Ultrasound examination showed a marked unilateral choroidal swelling. The magnetic resonance imaging lead to the diagnosis superior ophthalmic vein thrombosis. The medical examination revealed that the patient was Factor V Leiden heterozygote (APC-resistance).
Conclusions: An isolated superior ophthalmic vein thrombosis may be related to APC resistance.


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