Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Complications Following Intravitreal Administered Triamcinolone Acetonide

Müller M., Klär-Dißars U., Hoerauf H., Laqua H.
Universitätsklinikum Schleswig-Holstein, Campus Lübeck

Purpose: The intraocular injection of Triamcinolone Acetonide is a current approach, which is evaluated and used probationary for different diseases. The aim of this retrospective study was the evaluation of its complications.
Method: In 140 patients 4 mg TA was administered via pars plana in cases of cystoid macular edema of different origin (diabetic maculopathy, uveitis, pseudophakia, central vein occlusion, branch vein occlusion, exsudative age-related macular degeneration, idiopathic parafoveolar teleangiectasia). In 10 patients the injection was combined with intraocular surgery (e.g. vitrectomy, cataract surgery). The injection was repeated 1-2 times in 6 patients. The follow-up was 6 months at least.
Results: There were no complications during surgery. In 2 patients with a combined procedure a second vitrectomy with specimen and antibiotic rinsage was performed assuming endophthalmitis, with a culture-negative result. 3 patients with 'pseudo-hypopyon' and vitreous reaction got better with frequent controls without surgical intervention. 8 patients (5,7%) developed a secondary glaucoma which was treated with local antiglaucomatous drugs and in some cases with intermittent systemic dosage of acetazolamid. In 1 patient, which has had a vitrectomy in advance, an inferior retinal detachment occured.
Conclusions: The most frequent complications were intraocular irritations and


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