Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Intravitreal Triamcinolone Acetonide as Treatment of Neovascular Glaucoma

Heyer C., Kreissig I., Budde W. M., Degenring R. F.
Department of Ophthalmology and Eye Hospital, Faculty for Clinical Medicine Mannheim, Ruprecht-Karls-University, Heidelberg

Purpose: To evaluate safety and efficacy of intravitreal triamcinolone for treatment of neovascular glaucoma.
Method: The clinical interventional comparative case series study included 18 patients (18 eyes) with neovascular glaucoma due to proliferative diabetic retinopathy (n=11) or ischemic central retinal vein occlusion (n=7). All patients received an intravitreal injection of 25 mg of triamcinolone acetonide. The total study population was divided into a study group consisting of 5 eyes with an intravitreal injection and into a control group consisting of 13 eyes in which the intravitreal triamcinolone injection was combined with a peripheral circumferential transscleral retinal cryocoagulation. Mean follow-up was 5.4 ± 4.2 months. Main outcome measures were visual acuity, intraocular pressure, and degree of iris neovascularization.
Results: In the total study population, intraocular pressure was significantly (p=0.003) reduced from 35.9 ± 12.7 mm Hg preoperatively to 20.6 ± 11.0 mm Hg postoperatively. Degree of rubeosis iridis decreased significantly (p=0.02) from 2.7 ± 1.2 relative units to 1.3 ± 1.2 relative units. Group and control group did not vary significantly, best postoperative visual acuity (p=0.78), reduction in intraocular pressure (p=0.85) and decrease of the retinal neovascularisation (p=0,85).

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