|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Therapy of Degenerative and Dystrophic Corneal Diseases: Laser Treatment versus Keratoplasty
Duncker G. I. W.
The excimer laser offers today a broad range of treatment modalities for different anterior corneal dystrophies and many degenerative diseases of the cornea. The depth of the diseased anterior cornea should not exceed 100 microns for sccessful excimer laser surgery. We will discuss in our talk good examples of phototherapeutic treatment, but also cases in which lamellar or even penetrating keratoplasty are preferable. Best indications for PTK are scars which are limited to the anterior 50 to 100 microns of the cornea, cases of anterior dystrophies like those of Thiel-Behnke, Reis-Bückler or even superficial forms of macular or granular dystrophy. Fingerprint dystrophies are excellent candidates for PTK as well. Other indications are corneal amyloidosis, herpetic scars without vascularization, recurrent corneal erosions and surface irregularities. The most frequent refractive side effect of PTK treatment is a hyperopic shift corresponding to the depth of the performed ablation. The recurrence rate of corneal dystrophies after PTK treatment will be addressed.