Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Long-term Results of Scanning Laser Tomography and Polarimetry in NTG and POAG

Kremmer S., Niederdräing N., Hammerstein L., Darwesh S., Steuhl K.-P., Selbach J. M.
University Eye Clinic, Essen

Purpose: Recently, scanning laser tomography (SLT) for the evaluation of the optic disc and scanning laser polarimetry (SLP) for the analysis of the retinal nerve fiber layer have become increasingly important in glaucoma diagnostics. In this study, longterm results of SLT, SLP and ophthalmological standard examinations of NTG and POAG patients are demonstrated.
Method: 27 patients with NTG (average age 64.9, 13 male, 14 female) and 47 with POAG (age 64.3, m 26, f 21) were examined. Besides ophthalmological standard examinations including perimetry (Oculus, Twinfield 30°), SLT (TopSS, LDT, USA) and SLP (NFA II and GDx, LDT, USA) were performed. Follow-up period of the examinations was between 4 and 8 years (NTG 57.7 months, POAG 60 months).
Results: In NTG, the intraocular pressure was lowered from 13.2 mmHg to 12.6 mmHg (not significant ns) and in POAG from 18.1 to 15.2 mmHg (p<0,01). Perimetrical results revealed a slight increase of the mean defect (in NTG from 2.2. to 3.7; in POAG from 2.1 to 3.9), however statistically not significant. As one example for the various SLT parameters we mention here the neuroretinal rim area, which changed from 0.91 mm2 to 0.906 mm2 in NTG and from 0.84 mm2 to 0.8 mm2 in POAG (ns). Polarimetrical results showed a significant decrease of the superior average thickness in NTG (from 66.4 µm to 56

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