Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Impact of Preoperative Corneal Curvature on the Outcome of Penetrating Keratoplasty in Keratoconus

Nguyen N. X.1, Seitz B.1, Liu Y.1,2, Langenbucher A.1, Küchle M.1, Naumann G. O. H.1 
1Department of Ophthalmology, University of Erlangen-Nürnberg, Erlangen; 2Cornea Department, Tianjin Eye Hopital, Tianjin/TJ

Purpose: To assess the impact of the patient's preoperative corneal curvature on the refractive outcome after penetrating keratoplasty (PK) in keratoconus before and after suture removal.
Method: In this retrospective cross-sectional clinical study 236 keratoconus patients (mean age 37±11 years) were divided into 4 groups based on their preoperative keratometric (K-) readings: group 1: <50 diopters (D), (n=24); group 2: <60 D, (n=52); group 3: ³60 D, (n=101); group 4: irregular corneal shape with unmeasurable K-reading, (n=59). An 8.0/8.1mm central round PK was performed using 193 nm Meditec excimer laser trephination along metal masks with eight "orientation teeth/notches". A 16-bite double running cross-stitch suture was applied in all cases. Postoperative examinations were performed before removal of the first suture (i.e. 12 months) and after removal of the second suture (i.e. 18 months). The outcome measures included: central power (C-Power), keratometric astigmatism (AST), Surface Regularity Index (SRI), Surface Asymmetry Index (SAI), spherical equivalent (SEQ), refractive cylinder (Cyl), best-corrected visual acuity (BCVA). In addition, the


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