Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Prevention of Granular Corneal Dystrophy Recurrence with Soft Contact Lenses – A Long-term Control

Roters S., Severin M., Konen W., Krieglstein G. K.
Center of ophthalmology, University of Cologne, Germany

Purpose: Granular corneal dystrophy is usually treated sugically. Recurrences are common, and are observed irrespective of treatment method mostly after 2-5 years. We report the cases of 2 patients after penetrating keratoplasty (pk) and the followed by-treatment with soft contact lenses (cl).
Patient 1, male, familiar granular dystrophy: pK at the age of 54 (1982) followed by cataract extraction 16 month later. Aphakia was corrected with a soft contact lens (+13,0 dptr., 70% content of water, daily wear 12-14 h). At last follow-up, 19 years later, the corneal transplant was clear without a sign of recurrence. The other eye showed reappearance of granular dystrophy 7 years after penetrating keratoplasty. This fellow eye was implanted with an intraocular lens after cataract extraction, and therefore no contact lens was used in this eye.
Patient 2, female, familiar granular dystrophy: pK at the age of 61 (1998). Because of recurrence of granular lesions at the other eye 4 years after pk this eye was fitted with a contact lens for continuos wear (+0 dptr., DK 26.7, 70% content of water). There was no recurrence of the dystrophy now upto 60 months after surgery.
Conclusions: The effect of hydrophilic contact lenses with reduced inclusion of granular lesions has been published 1991 by HU Moller. The effect of soft contact lenses in treatment and prevention of A

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