Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Relevance of the Electroretinogram for the Management of Ischemic Retinal Diseases

Rüther K. 
Augenklinik, Charité Campus Virchow-Klinikum, Humboldt-Universität zu Berlin

Purpose: The Ganzfeld-Electroretinogram (ERG) renders information about the retinal ischemic damage. The most important parameters are the ratio of the scotopic b- and a-wave amplitude, the oscillatory potentials and the implicit times of the cone ERG.
Method: The Ganzfeld-Electroretinogram (ERG) renders information about the retinal ischemic damage. The most important parameters are the ratio of the scotopic b- and a-wave amplitude, the oscillatory potentials and the implicit times of the cone ERG.
Results: The ischemic damage caused by a central retinal artery occlusion correlates well with the attenuation of the scotopic b-wave amplitude resulting in a reduced b/a amplitude ratio. In addition, occasional damage of the outer retina leading to neovascularisation can be recognised. In cases of central retinal vein occlusions the ERG changes are associated to the damage seen in fluoresceine angiography. However, if angiography is hard to evaluate, the oscillatory potentials as well as the cone implicit times help to quantify the ischemic damage. By this, the risk of neovascularisation can be appreciated.
Conclusions: Electroretinography is a valuable tool for the management of retinal vessel occlusions. In conjunction with the angiography it helps to make therapeutical decisions. For the management of diabetic retinopathy the ERG has not shown to be of significance so far.


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