Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Surgical Treatment of Vasoproliferative Tumors in Coats Disease

Feudner E., Gelisken F., Besch D., Bartz-Schmidt K. U.
Department of Ophthalmology I, University of Tuebingen

Purpose: Advanced Coats disease may show massive exsudation leading to intra- and subretinal lipid deposition and exsudative retinal detachment. A rare complication in Coats disease is the development of a secondary vasoproliferative tumor. We report on the surgical procedure and results in two patients with exsudative retinal detachment and a vasoproliferative tumor secondary to Coats disease.
Method: We report on two male patients (aged 9 and 30 years) who were first seen 2001 and 2002 with unilateral progressive loss of visual acuity. Visual acuity was 5/125 and 5/100 respectively. Advanced Coats disease with massive intra- and subretinal exsudation, exsudative retinal detachment and a secondary vasoproliferative tumor in the inferior quadrant was diagnosed in both patients. Initial treatment consisted of cryotherapy and laser photocoagulation. In one patient visual acuity transiently increased to 20/200 but decreased again with progression of the retinal detachment. In the other patient visual acuity decreased further to counting fingers due to increasing involvement of the macula by subretinal lipid exsudation. Due to progression of the disease and subsequent decrease of visual acuity vitreo-retinal surgery was performed five and six months after the initial presentation respectively. Surgical treatment included pars plana vitrectomy, retinectomy, endoresection of the vasoproliferative tumor,

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