Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Effect of Vitrectomy with Membrane Peeling on Functional Results in Patients with Chronic Uveitis and Cystoid Macular Edema

Müller B., Torun N., Velhagen K. H., Hartmann C., Pleyer U.
Dept. Ophthalmology, Charité-Campus Virchow Hospital, Humboldt University of Berlin

Purpose: To investigate the effect of epiretinal and internal limiting membrane peeling on chronic cystoid macular edema (CME) in recurrent uveitis.
Method: In 2001-2002 26 Patients with recurrent Uveitis und refractory cystoid macular edema and media opacities underwent pars plana vitrectomy. In 13 eyes vitrectomy was performed without surgical manipulation of the macula. Peeling of epiretinal membranes was performed in 8 eyes and an additional peeling of the internal limiting membrane 12 eyes. In 8 eyes vitrectomy was combined with pars plana lentectomy.
Results: Three months postoperatively an average increase in visual acuity of 1.5 lines was observed. In 15 eyes an increase of two or more lines was achieved. Peeling of macular pucker and internal limiting membranes consolidates macular morpholgy, but did not led to a significant increase in visual acuity. The largest increase in visual acuity was achieved in combined pars plana lentectomy. Recurrences in uveitis were not observed during the postoperative period while immunsuppressive therapy was maintained.
Conclusions: Patients with recurrent uveitis and refractory cystoid macular edema benefit from pars plana vitrectomy with a moderat increase in visual acuity. Peeling of epiretinal membranes and internal limiting membrane has been

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