Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Stargardt’s Disease in Stadtler’s Classification

Pojda-Wilczek D., Pojda S. M., Herba E., Plech A. R., Makowiecka-Obidzińska K., Jędrzejewski W., Zatorska B.
Department of Ophthalmology and Eye Clinic Division of the Municipal Hospital nr 1 in Bytom, Medical University of Silesia, Katowice/PL

Purpose: The aim of this study is to check the usefulness of Stadtler’s classification in various forms of Stargardt’s disease.
Method: Stargardt’s disease was diagnosed in 18 patients (6 female, 12 male), aged from 6 to 64 (mean 20), who were examined for bilateral decreased visual acuity, retinal degeneration or Stargardt’s disease found in their relatives. The diagnosis was based on clinical and electrophysiologic examinations (visual evoked potentials – VEP, full-field flash electroretinography – ERG, focal electroretinography – focal ERG, electrooculography – EOG) and fluorescein angiography. The patients were divided into 4 groups according to Stadtler’s criteria. The results between the groups were compared with one another and with normal values. Newman-Keuls test was used for statistic analysis.
Results: Using Stadler’s criteria each patient could be classified with a relevant group. The best visual acuity was found in the patients of group 1 with benign concentric pigment epithelium layer defects in macular region. The earliest onset of visual problems was found in the patients of group 2 – the classical Stargardt’s central dystrophy with or without fundus flavimaculatus of the peripheral retina. The patients of this group and of group 3 – „cone dystrophy

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