Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Correlation between Different Quantitative Parameters in Open-angle Glaucoma

Marcu C., Danielescu C., Nitu M., Chiselita D. 
Universitatea de Medicina si Farmacie “Gr. T. Popa”, Clinica I Oftalmologie, Iasi, Romania

Purpose: To establish correlation between C/D ratio, visual field and IOP in open angle glaucoma patients treated medically or/and surgically.
Method: Retrospective study that included 34 eyes with open angle glaucoma (22 POAG, 12 pseudoexfoliative) on a mean follow-up period of 24.5 months. We have registered the next parameters, at the first presentation and at the follow-up visits: C/D ratio, PSD, MD, IOP, visual acuity.
Results: In the study group there was a good correlation between C/D and PSD (r = 0.536); the correlation was better in pseudoexfoliative glaucoma patients (r = 0.615) compared to POAG patients (r = 0.461). There was a good correlation between visual acuity and MD in the study group (r = 0.440); the correlation was obvious in POAG patients (r = 0.510). In multistratified analysis, the best C/D - PSD correlation was in the group that had C/D ratio between 0.4 – 0.8 and in the group with PSD between 4 and 8 dB. In 16 eyes (47.06%) there were no signs of disease progression; in 18 eyes there were signs of progression (perimetric 14.70%, papilo-perimetric 38.23%). There was a significant correlation between the disease evolution and the therapeutically induced IOP (mean IOP in the stationary disease group – 18.72 mmHg compared to a mean IOP of 21.32 mmHg in the progressive disease group).
Conclusions: There

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