Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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Influence of Central Corneal Thickness and Myopia on Changes in Measurement of Retinal Thickness after LASIK

Hoffmann E. M., Dick H. B., Grus F. H., Pfeiffer N.
Departement of Ophthalmology, University of Mainz

Purpose: The Retinal Thickness Analyzer (RTA), scanning laser ophthalmoscope, allows to measure the retinal thickness peripapillary and at the posterior pole. It is based on a green helium- neon laser of 540 nm, and generates cross-sections of the retinal thickness. The aim of this study was to evaluate, if changes in retinal thickness measurements after LASIK are correlated with central corneal thickness and myopia.
Method: 52 eyes of 27 healthy volunteers were included in the study. Before LASIK a pachymetry and a measurement of the retinal thickness were performed. One week after LASIK analysis with the RTA was repeated.
Results: The postoperative measurement of retinal thickness revealed a significant decrease in mean retinal nerve fiber layer (p<0.05 preoperative: 0.18mm± SE 0.025mm, postoperative: 0.12mm± SE 0.01mm). There was no correlation between decrease in measurement of retinal thickness and central corneal thickness (r=-0.1, p> 0,05). However, the higher the myopia, the higher were the measured changes in retinal nerve fiber layer thickness after LASIK (r=0.46, p<0.05).
Conclusions: The decrease in nerve fiber layer measurements after LASIK does not correlate with central corneal thickness. But there is a significant correlation between changes in retinal thickness after LASIK and myopia, although the correlation is weak. Con

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