Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"

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The Influence of Cataract Surgery on the Course of Age-Related Macular Degeneration – First Experience from the “ECAM” Study

Brunner S.1, Falkner C.1, Krebs I.1, Stolba U.1, König F.2, Bauer P.2, Binder S.1
1Department of Ophthalmology at the Rudolf-Stiftung Hospital, Vienna, Austria; 2Institute for Medical Statistics and Documentation, Vienna, Austria

Purpose: Senile cataract and age-related macular degeneration (AMD) are the most common causes for blindness and visual impairment in people over 60 years. As a growing coincidence is seen in both diseases, there is still much uncertainty about the usefulness of cataract surgery in coexistent AMD. In the literature, the relationships between cataract and AMD are not clear; it looks like that advanced stages of AMD, e.g. CNV or geographic atrophy, have a tendency to progress after cataract surgery.
Method: The ongoing ECAM trial is a randomised prospective study , scheduled for 3 years. In our center, 80 patients will be included. The challenge is to find out if cataract surgery might influence the course of coexisting non-exsudative AMD. Patients are randomized into an early-surgery group and a control group, respectively. After a follow-up for 6 months, functional results and digitized images are analyzed.
Results: In our center, 20 eyes of 20 patients were included until march 2003; the average age was 80.8 years. In the early-surgery group (n=9), an increase in distance acuity from logMAR 0,64 (0.4-0.82) to lo

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