Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


Hotelbuchung
   Hotel Registration
Grußwort
   Welcome address
Beteiligte Gesellschaften
   Societies involved
DOG Information
   DOG Information
Eröffnung des Kongresses
   Opening Ceremony
Preise
   Awards
Ablauf der Tagung 2003
   General overview of congress
Lageplan der Räumlichkeiten
   Map of Congress Center
Wissenschaftliche Themen
   Scientific topics
Symposien
   Symposia
Wissenschaftliches Programm
   Scientific program
Posterpräsentationen
   Poster Presentation
Kurse
   Courses
Begleitende Veranstaltungen
   Accompanying program
Arbeitssitzungen
   Working sessions
Rahmenprogramm
   Social program
Allgemeine Informationen
   General Information
Autorenindex
   Index of Authors
Industrieaussteller
   Commercial exhibitors
Sponsoren
   Sponsors
Impressum



DOG Homepage


Abstract
Abstract

Age-related Macular Degeneration: the Antioxidant Systems

Darabă O., Popovici I.
Universitatea de Medicină şi Farmacie, Clinica II Oftalmologie Iaşi, România

Purpose: This study is based on the particularities of oxidative stress induced by age- related macular degeneration (ARMD), cataract or both ARMD and cataract considering the production of superoxide anion O2, initiator of reactive oxygen species and free radicals. We studied the antioxidant systems, in order to establish a correlation between these enzymes and the occurrence of ARMD and cataract diseases.
Method: The comparative study of the main blood enzymatic oxidative stress markers (superoxide dismutase, catalase and glutathione peroxidase) was done on four series of patients, both males and females aged of 50-80 years old.
Series I: 40 patients (30 females and 10 males) diagnosed with ARMD; series II: 35 patients (20 females and 15 males) diagnosed with ARMD and cataract; series III: 40 patients (25 females and 15 males) diagnosed with cataract and 30 healthy individuals (15 females and 15 males) as control group. The patients with systemic diseases such as: diabetes, hypertension, hyperlipemia or with other ocular diseases were excluded.
Results: The group of subjects diagnosed with ARMD (series I) the antioxidant systems were significantly decreased compared with the subjects diagnosed with cataract (series III). The antioxidant systems of the subjects diagnosed with both ARMD and cataract (series II) were decreased compared with the subjects diagnosed with ca


Zurück | Back