|Programm||"Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"|
Online Autofluorescence Measurements during Selective RPE Laser Treatment (SRT)
Framme C.1, Schüle G.2, Roider J.3, Birngruber R.2, Brinkmann R.2
Purpose: By using a train of microsecond laser pulses a selective RPE treatment (SRT) of macular diseases is possible while sparing the adjacent photoreceptors and avoiding scotoma. A problem is the non-visibility of the laser lesions due to a lack of thermal damage to the retina. Therefore invasive fluorescein-angiography is necessary to confirm RPE damage by leakage. It is supposed that the autofluorescent properties of the aging pigment lipofuscin, contained in the RPE cells, changes during laser treatment. The aim of the study was to evaluate the value of the autofluorescence changes as a non-invasive treatment control during selective RPE laser treatment.