Programm                 "Degeneration und Regeneration– Grundlagen, Diagnostik und Therapie"


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Abstract
Abstract

Changes of the Electro-Oculogram after 360° Retinotomy and Macular Translocation for Subfoveal Choroidal Neovascularisation in Age-Related Macular Degeneration

Lüke C., Alteheld N., Aisenbrey S., Lüke M., Walter P., Kirchhof B.
Centre of Ophthalmology, Cologne University

Purpose: To evaluate potential electro-oculographic changes after 360° retinotomy and macular translocation for subfoveal choroidal neovascularisation in patients with age-related macular degeneration (AMD) in a prospective nonrandomized comparative (self-controlled) trial.
Method: A consecutive series of 30 patients suffering from subfoveal choroidal neovascularisation secondary to age-related macular degeneration underwent 360° retinotomy and macular translocation. The EOG served as the main parameter of the study and was recorded one day prior to the translocation surgery and no earlier than 21 days after the silicone oil removal.
Results: Postoperatively, a statistically significant decrease in mean dark trough by 64% was found for treated eyes (p<0.001). The mean dark trough of the fellow eye remained stable after surgery (p=0.33). The postoperative difference between the treated und untreated eyes proved to be statistically significant (p<0.001). The Arden ratio remained stable in the treated and untreated eyes with mean values of 204% (p=0.81) and 213% (p=0.18), respectively. A significant correlation between the reduction of the dark trough and the visual acuity at the one year follow-up was found.
Conclusions: A persistant decrease in the corneofundal potential is associ


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